There are several excellent resources available to provide both background on group sequential design methods and examples of planning and analyses using R:
- The
rpact
package for group sequential designs - The
gsDesign
package for group sequential designs- Group Sequential Designs Made Easy by Keaven Anderson and Nan Xiao
Since group sequential design methodology can also implemented in information monitoring trials, users should understand the fundamentals of these designs.
Using impart
There are several vignettes built into impart
: these
include vignettes on information monitoring designs as well as group
sequential designs. To see all available vignettes in impart, use the
vignettes
command:
If you are using impart
in practice, please
citation(package = "impart")
#> To cite package 'impart' in publications use:
#>
#> Van Lancker K, Betz J, Rosenblum M (2024). _impart: Information
#> Monitoring for Precision Adaptive Randomized Trials_. R package
#> version 0.1.0, https://github.com/jbetz-jhu/impart,
#> <https://jbetz-jhu.github.io/impart/>.
#>
#> A BibTeX entry for LaTeX users is
#>
#> @Manual{,
#> title = {impart: Information Monitoring for Precision Adaptive Randomized Trials},
#> author = {Kelly {Van Lancker} and Josh Betz and Michael Rosenblum},
#> year = {2024},
#> note = {R package version 0.1.0,
#> https://github.com/jbetz-jhu/impart},
#> url = {https://jbetz-jhu.github.io/impart/},
#> }