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All functions

apply_stopping_rule_z()
Apply group sequential stopping rules to test statistics
asymptotic_information_difference_means() asymptotic_information_difference_proportions()
Approximate information from a random samples of a given size for continuous and binary outcomes
asymptotic_information_mann_whitney_fm()
Approximate information from a random samples of a given size for ordinal outcomes
calculate_covariance()
Compute bootstrap covariance of estimates
calculate_estimate()
Compute an estimate from a wrapper function
colon_cancer
colon_cancer: Processed Moerton Colon Cancer Data
compute_bootstrap_serial() compute_bootstrap_parallel()
Compute bootstrap from a vector of IDs
correct_one_sided_gsd()
Correct one-sided trialDesignGroupSequential object
count_outcomes()
Count outcome events from prepared study data
count_outcomes_at_time_t()
Reconstruct the count of events at a given study time during a study
data_at_time_t()
Reconstruct data available at an earlier point in a study
estimate_information()
Estimate the observed information level
example_1
Example 1: Simulated Trial with a Single, Continuous Outcome
example_1_final
Example 1: Simulated Trial with a Single, Continuous Outcome - Final Analysis
example_1_ia_1
Example 1: Simulated Trial with a Single, Continuous Outcome - Interim Analysis 1
example_1_ia_2
Example 1: Simulated Trial with a Single, Continuous Outcome - Interim Analysis 2
information_to_n_continuous_1_to_1() information_to_n_binary_1_to_1()
Convert information level into an approximate sample size requirement for a one-stage design
information_trajectory()
Reconstruct a trajectory of information accrual
initialize_monitored_design()
Initialize an Information Monitoring Design
monitored_analysis()
Perform pre-specified analyses for an interim monitored trial design
monitored_analysis_control() monitored_analysis_control_testing()
Control arguments for performing information monitored analyses
monitored_design_checks()
Check consistency of a monitored_design object
mw_from_pmfs()
Title Compute the Mann-Whitney estimand from Probability Mass Functions
orthogonalize_estimates()
Orthogonalize estimates and covariance matrix
plot_outcome_counts()
Produce a cumulative plot of study events
prepare_monitored_study_data()
Prepare monitored study data for monitoring and analysis
relabel_by_id()
Create relabeled dataset from a list of resampled IDs
required_information_single_stage() required_information_mw_single_stage()
Determine the information level required for a one-stage, fixed sample size design
required_information_sequential()
Adjust Information for Interim Monitoring
standardization() standardization_correction()
Compute stanadardization (i.e. G-Computation) estimator