Package index
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apply_stopping_rule_z() - Apply group sequential stopping rules to test statistics
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asymptotic_information_difference_means()asymptotic_information_difference_proportions()asymptotic_information_risk_difference()asymptotic_information_relative_risk() - Compute Approximate Information from Sample Size: Continuous & Binary Outcomes
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asymptotic_information_logrank() - Compute Approximate Information from Event Counts: Log Hazard Ratio
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boot_control()boot_control_testing() - Parameters for using boot::boot() in Non-Sequential Analyses
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calculate_covariance() - Compute bootstrap covariance of estimates
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calculate_estimate() - Compute an estimate from a wrapper function
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compute_bootstrap_serial()compute_bootstrap_parallel() - Compute bootstrap from a vector of IDs
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correct_one_sided_gsd() - Correct one-sided trialDesignGroupSequential object
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count_outcomes() - Count outcome events from prepared study data
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count_outcomes_at_time_t() - Reconstruct the count of events at a given study time during a study
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data_at_time_t() - Reconstruct data available at an earlier point in a study
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dr_wls()dr_wls_fit() - Doubly Robust Estimation Using Joffe's Doubly Robust Weighted Least Squares (DR-WLS) Estimator
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estimate_information() - Estimate the observed information level
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example_1 - Example 1: Simulated Trial with a Single, Continuous Outcome
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example_1_final - Example 1: Simulated Trial with a Single, Continuous Outcome - Final Analysis
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example_1_ia_1 - Example 1: Simulated Trial with a Single, Continuous Outcome - Interim Analysis 1
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example_1_ia_2 - Example 1: Simulated Trial with a Single, Continuous Outcome - Interim Analysis 2
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hr_events()hr_power()hr_alpha()hr_minimal()hr_design() - Design Calculations for a Hazard Ratio Estimand
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impute_covariates_mean_mode() - Impute missing baseline covariates using mean/mode imputation
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required_information_sequential()get_gsd_inflation_factor() - Adjust Information Target for a Group Sequential Design
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information_to_n_difference_means()information_to_n_risk_difference()information_to_n_relative_risk()information_to_events_log_hr() - Convert Information Target into Sample Size for Fixed N Single-Stage Design
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information_trajectory() - Reconstruct a trajectory of information accrual
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initialize_monitored_design() - Initialize an Information Monitoring Design
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asymptotic_information_mann_whitney_fm()mw_from_pmfs() - Compute Approximate Information from Sample Size: Mann-Whitney Estimand
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monitored_analysis() - Perform pre-specified analyses for an interim monitored trial design
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monitored_analysis_control()monitored_analysis_control_testing() - Control arguments for performing information monitored analyses
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monitored_design_checks() - Check consistency of a
monitored_designobject
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orthogonalize_estimates() - Orthogonalize estimates and covariance matrix
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plot_outcome_counts() - Produce a cumulative plot of study events
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prepare_monitored_study_data() - Prepare monitored study data for monitoring and analysis
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relabel_by_id() - Create relabeled dataset from a list of resampled IDs
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required_information_single_stage()required_information_mw_single_stage() - Determine the information level required for a one-stage, fixed sample size design
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rr_n_per_arm()rr_power()rr_alpha()rr_minimal()rr_design() - Design Calculations for a Relative Risk Estimand
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sim_colon_cancer - sim_colon_cancer: Processed Moerton Colon Cancer Data
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speffsurv_impart() - Wrapper for speff2trial::speffsurv: See speff2trial::speffSurv
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standardization()standardization_fit()standardization_influence()standardization_df_adjust_tsiatis_2008() - Estimate Treatment Effect using Marginal Standardization (G-Computation)
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test_data - test_data: A dataset used for testing package functions